Dr. Bruce Zuraw
Dr. Zuraw is a Professor of Medicine in the Division of Rheumatology, Allergy, and Immunology in the Department of Medicine, UC San Diego. He is the Director of the Section of Allergy and Immunology at the Veterans Affairs San Diego Healthcare System and Director of the Angioedema Center.
Dr. Zuraw is also the inaugural holder of the US Hereditary Angioedema Association (HAEA) Endowed Chair.
About the Lab
The Zuraw lab conducts research in angioedema and asthma. Angioedema studies explore bradykinin-mediated swelling, genetic determinants of angioedema severity, and the role of bradykinin receptors, alongside investigating improved diagnostic assays. Asthma studies focus on the airway epithelial cell's role in inflammatory airway disease, examining glucocorticoid-induced leucine zipper (GILZ) impact on airway inflammation and the involvement of B2 and B1 bradykinin receptors and transient receptor potential channels in allergic airway inflammation.
Research Highlights
- Establishment of the US HAEA Angioedema Center at UCSD, slated to open in the Spring of 2014.
- Hereditary angioedema with normal C1 inhibitor function: consensus of an international expert panel. Allergy Asthma Proc. 33:S145, 2012.
- Corticosteroid-induced gene expression in allergen-challenged asthmatic subjects taking inhaled budesonide. Br. J. Pharmacol. 165:1737, 2012.
- Supported by grants from the NIH, DOD, and VA.